NBC’s hit family drama, This Is Us, returns for its fourth season on Sept. 24.

But first, the network unveiled the first look over Labor Day weekend, which introduces a slew of new characters to the series.

As Mandy Moore’s character reflects on the unexpected moments in life, we see clips of Once Upon a Time’s Jennifer Morrison, Shooter’s Omar Epps, When They See Us’ Marsha Stephanie Blake and Asante Blackk and more.

On top of that, the trailer teases an upcoming surprise in the forthcoming season.

“If you think you know what’s coming next, you don’t know Us,” the spot reveals.

This Is Us returns with a special extended premiere Sept. 24 at 9 p.m. ET/PT

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